IBUPROFEN (Motrin®, Advil®, Rufen®, Nuprin®) is an antiinflammatory drug. Ibuprofen reduces inflammation and eases mild to moderate pain. It reduces fever and relieves the symptoms of rheumatoid arthritis (rheumatism), osteoarthritis, menstrual cramps or premenstrual pain and swelling.

Quantity	Dosage	Per pill	Price(usd)
20 Pills	Ibuprofen 200mg	$3.00	$59.95
50 Pills	Ibuprofen 200mg	$1.80	$89.95
100 Pills	Ibuprofen 200mg	$1.40	$139.95
20 Pills	Ibuprofen 400mg	$3.50	$69.95
50 Pills	Ibuprofen 400mg	$2.00	$99.95
100 Pills	Ibuprofen 400mg	$1.60	$159.95
20 Pills	Ibuprofen 600mg	$4.00	$79.95
50 Pills	Ibuprofen 600mg	$2.40	$119.95
100 Pills	Ibuprofen 600mg	$1.90	$189.95

Uses

Ibuprofen belongs to a class of drugs called non-steroidal anti-inflammatory drugs (NSAIDs). Other members of this class include naproxen (Aleve), indomethacin (Indocin), nabumetone (Relafen) and several others. These drugs are used for the management of mild to moderate pain, fever, and inflammation. Prostaglandins are chemicals that are made by the body and are responsible for causing pain, fever and inflammation. Ibuprofen blocks the enzyme that makes prostaglandins (cyclooxygenase), resulting in lower levels of prostaglandins. As a consequence, inflammation, pain and fever are reduced. The FDA approved ibuprofen in 1974.

Directions

Take ibuprofen tablets or caplets by mouth. Follow the directions on the label. Swallow tablets whole with a full glass of water; take tablets in an upright or sitting position. Taking a sip of water first, before taking the tablets, may help you swallow them. If possible take bedtime doses at least 10 minutes before lying down. Ibuprofen may be taken with food if it upsets your stomach. Take your doses at regular intervals. Do not take your medicine more often than directed.

Contact your pediatrician or health care professional regarding the use of this medicine in children. Special care may be needed

Side efects

The most common side effects from ibuprofen are rash, ringing in the ears, headaches, dizziness, drowsiness, abdominal pain, nausea, diarrhea, constipation and heartburn. Ibuprofen may cause ulceration of the stomach or intestine, and the ulcers may bleed. Sometimes, ulceration and bleeding can occur without abdominal pain, and black tarry stools, weakness, and dizziness upon standing (orthostatic hypotension) may be the only signs of a problem. NSAIDs reduce the flow of blood to the kidneys and impair function of the kidneys. The impairment is most likely to occur in patients with preexisting impairment of kidney function or congestive heart failure, and use of NSAIDs in these patients should be done cautiously. People who are allergic to other NSAIDs, including aspirin, should not use ibuprofen. Individuals with asthma are more likely to experience allergic reactions to ibuprofen and other NSAIDs

Precautions

Tell your doctor if you have any of these conditions:
•anemia
•asthma, especially aspirin sensitive asthma
•bleeding problems or taking medicines that make you bleed easily such as anticoagulants ('blood thinners')
•cigarette smoker
•diabetes
•drink more than 3 alcohol-containing beverages a day
•heart failure
•high blood pressure
•kidney disease
•liver disease
•stomach or duodenal ulcers
•systemic lupus erythematosus
•ulcerative colitis
•an unusual or allergic reaction to aspirin, other salicylates, other NSAIDs, other medicines, foods, dyes or preservatives
•pregnant or trying to get pregnant
•breast-feeding

Drug Interactions

Ibuprofen is associated with several suspected or probable interactions that can affect the action of other drugs. Ibuprofen may increase the blood levels of lithium (Eskalith) by reducing the excretion of lithium by the kidneys. Increased levels of lithium may lead to lithium toxicity. Ibuprofen may reduce the blood pressure-lowering effects of drugs that are given to reduce blood pressure. This may occur because prostaglandins play a role in the regulation of blood pressure. When ibuprofen is used in combination with aminoglycosides (e.g., gentamicin) the blood levels of the aminoglycoside may increase, presumably because the elimination of aminoglycosides from the body is reduced. This may lead to aminoglycoside-related side effects. Individuals taking oral blood thinners or anticoagulants (e.g., warfarin) should avoid ibuprofen because ibuprofen also thins the blood, and excessive blood thinning may lead to bleeding.

Overdose

Any medication taken in excess can have serious consequences. An overdose of Motrin can be fatal. If you suspect an overdose, seek medical attention immediately.

Symptoms of Motrin overdose may include:
Abdominal pain, breathing difficulties, coma, drowsiness, headache, irregular heartbeat, kidney failure, low blood pressure, nausea, ringing in the ears, seizures, sluggishness, vomiting

Missed Dosage

Not Applicable

Storage

Ibuprofen should be stored at room temperature, between 15-30°C (59-86°F).